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Coronary-Artery Aneurysm in Tocilizumab-Treated Children with Kawasaki’s Disease
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2017-11-08 , DOI: 10.1056/nejmc1709609
Tomo Nozawa , Tomoyuki Imagawa , Shuichi Ito

Four patients with Kawasaki’s disease resistant to IVIG treatment had a response to the anti–interleukin-6 antibody tocilizumab, but coronary-artery aneurysms developed in two of the patients. Such aneurysms occur at very low frequency among patients who receive this treatment.

中文翻译:

川崎病合并托珠单抗治疗的儿童冠状动脉瘤

四名对IVIG治疗有抵抗力的川崎病患者对抗白介素6抗体妥珠单抗有反应,但其中两名患者出现了冠状动脉瘤。在接受这种治疗的患者中,这种动脉瘤的发生频率非常低。
更新日期:2017-11-09
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