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Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass
The New England Journal of Medicine ( IF 158.5 ) Pub Date : 2017-11-08


To the Editor: Shroyer et al. (Aug 17 issue)1 report the 5-year outcomes of the Randomized On/Off Bypass (ROOBY) trial. They conclude that off-pump coronary-artery bypass grafting (CABG) led to lower rates of 5-year survival and event-free survival than on-pump CABG. Although the authors allude to criticism of the trial design that allowed inexperienced surgeons to participate in the off-pump part of the trial, this Achilles’ heel is inadequately explored. The sensitivity analysis, excluding numerous off-pump–to–on-pump conversions (12.4%, vs. a 2.2% national average; the higher rate is a surrogate marker of inexperience) obviated the risk from off-pump CABG. The authors . . .

中文翻译:

体外循环和体外循环冠状动脉旁路手术后的五年结果

致编辑:Shroyer等。(8月17日发行)1报告了随机开/关绕过(ROOBY)试验的5年结果。他们得出的结论是,非体外循环冠状动脉旁路移植术(CABG)导致的5年生存率和无事件生存率低于体外循环CABG。尽管作者暗示了对试验设计的批评,该试验设计允许经验不足的外科医生参与试验的非常规部分,但这种跟腱的脚跟并未得到充分研究。敏感性分析排除了无数次由泵到泵的转换(12.4%,而全国平均水平为2.2%;较高的比率是缺乏经验的替代标志),避免了由泵外CABG带来的风险。作者。。。
更新日期:2017-11-09
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