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Notching up B-cell pathology in chronic GVHD
Blood ( IF 20.3 ) Pub Date : 2017-11-09 , DOI: 10.1182/blood-2017-09-805366
Vedran Radojcic 1 , Leo Luznik 2
Affiliation  

In this issue of Blood , Poe et al identify the pathogenic and druggable B-cell receptor (BCR)–Notch axis as a feed-forward loop in patients with chronic graft-versus-host disease (cGVHD), providing a rationale and methods for its therapeutic targeting. 1

中文翻译:

在慢性 GVHD 中发现 B 细胞病理

在本期血液中,Poe 等人将致病性和可药物性 B 细胞受体 (BCR)–Notch 轴确定为慢性移植物抗宿主病 (cGVHD) 患者的前馈回路,提供了原理和方法其治疗靶向。1
更新日期:2017-11-09
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