There is conflicting evidence, relying on heterogeneous studies, as to whether aldosterone excess is responsible for an increased risk of cardiovascular and cerebrovascular complications in patients with primary aldosteronism. We aimed to assess the association between primary aldosteronism and adverse cardiac and cerebrovascular events, target organ damage, diabetes, and metabolic syndrome, compared with the association of essential hypertension and these cardiovascular and end organ events, by integrating results of previous studies.

中文翻译：

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与原发性高血压相比，原发性醛固酮增多症的心血管事件和靶器官损害：系统评价和荟萃分析。

依靠异质性研究，关于原发性醛固酮增多症患者中醛固酮过量是否会增加心血管和脑血管并发症的风险，存在相互矛盾的证据。我们旨在通过整合先前研究的结果，评估原发性醛固酮增多症与不良心脏和脑血管事件，靶器官损害，糖尿病和代谢综合征之间的关联，并将其与原发性高血压与这些心血管和终末器官事件的关联进行比较。