Model Studies for the Preparation of Oxepanes and Fused Compounds by Tandem [4+3] Cycloaddition/Ring-Opening Metathesis/Cross Metathesis,European Journal of Organic Chemistry

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Model Studies for the Preparation of Oxepanes and Fused Compounds by Tandem [4+3] Cycloaddition/Ring-Opening Metathesis/Cross Metathesis
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-11-07 03:02:00 , DOI: 10.1002/ejoc.201700994
Paolo Disetti ₁ , Linda Piras ₂ , Maria Moccia ₂ , Michele Saviano ₂ , Mauro F. A. Adamo ₁

Affiliation

The preparation of cyclic-ether building blocks has been achieved through [4+3] oxyallyl cycloaddition and a ring-opening-metathesis/cross-metathesis process. These compounds are useful intermediates for organic synthesis with potential applications in natural product synthesis and fragment-based drug discovery.

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