当前位置: X-MOL 学术Biomacromolecules › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A Bottom-Up Synthesis of Vinyl-Cellulose Nanosheets and Their Nanocomposite Hydrogels with Enhanced Strength
Biomacromolecules ( IF 5.5 ) Pub Date : 2017-11-03 00:00:00 , DOI: 10.1021/acs.biomac.7b01224
Jianquan Wang 1, 2 , Jiabao Niu 1 , Toshiki Sawada 2 , Ziqiang Shao 1 , Takeshi Serizawa 2
Affiliation  

Extracted nanocellulose from natural resources commonly requires modification before it is used as an effective nanofiller. In the present study, through an enzymatic polymerization of α-d-glucose 1-phosphate from the primer 2-(glucosyloxy)ethyl methacrylate (GEMA), a novel type of two-dimensional methacrylate-containing cellulose nanosheets (CNS) with a thickness of about 6 nm, named as GEMA-CNS, was directly synthesized under a mild condition by a “bottom-up” method. The structure and morphology of GEMA-CNS were characterized by 1H-nuclear magnetic resonance (NMR), matrix-assisted laser desorption/ionization time-of-flight mass spectra (MALDI-TOF MS), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and atomic force microscopy (AFM). Afterward, the obtained GEMA-CNS was covalently incorporated into poly(ethylene glycol) matrix through thiol–ene Michael addition, fabricating a series of GEMA-CNS-based nanocomposite hydrogels. The addition of GEMA-CNS effectively improved the mechanical strength and altered the internal network structures of hydrogels; additionally, the swelling/biodegradation behaviors of gels in phosphate buffer saline (pH 7.4) at 37 °C were affected to some degree. This species of property-tunable hydrogels with GEMA-CNS dosage demonstrates potential applications in tissue engineering. The current presentation opens a new road for direct enzymatic preparation of reactive nanocellulose and its novel applications in nanocomposite materials.

中文翻译:

自底向上合成乙烯基纤维素纳米片及其强度增强的纳米复合水凝胶

从自然资源中提取的纳米纤维素通常需要进行修饰,才能用作有效的纳米填料。在本研究中,通过从底漆2-(葡糖氧基)甲基丙烯酸乙酯(GEMA)酶促聚合α - d-葡萄糖1-磷酸,一种新型的具有一定厚度的二维含甲基丙烯酸的纤维素纳米片(CNS)通过“自下而上”的方法在温和条件下直接合成了约6 nm的GEMA-CNS。GEMA-CNS的结构和形态由1表征H核磁共振(NMR),基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS),傅里叶变换红外(FTIR)光谱,X射线衍射(XRD),透射电子显微镜( TEM和原子力显微镜(AFM)。然后,将获得的GEMA-CNS通过硫醇-烯迈克尔加成共价结合到聚乙二醇中,从而制造出一系列基于GEMA-CNS的纳米复合水凝胶。GEMA-CNS的添加有效地提高了机械强度,并改变了水凝胶的内部网络结构;此外,凝胶在37°C的磷酸盐缓冲盐水(pH 7.4)中的溶胀/生物降解行为受到一定程度的影响。具有GEMA-CNS剂量的这种性质可调的水凝胶证明了在组织工程中的潜在应用。
更新日期:2017-11-05
down
wechat
bug