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Bis-Acetyl Carbazole: A Photoremovable Protecting Group for Sequential Release of Two Different Functional Groups and Its Application in Therapeutic Release
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-11-03 08:54:44 , DOI: 10.1002/ejoc.201701253
Yarra Venkatesh 1 , Surajit Nandi 1 , Maniklal Shee 1 , Biswajit Saha 2 , Anakuthil Anoop 1 , N. D. Pradeep Singh 1
Affiliation  

Bis-acetyl carbazole-based fluorescent photoremovable protecting groups (FPRPG) have been synthesized and used for the sequential release of two different functional groups such as carboxylic acids, alcohols, thiols, and amines. Studies on a synthesized drug delivery system (DDS) demonstrated the applicability of the dual release ability of our system in vitro.

中文翻译:

双乙酰咔唑:两个不同官能团的顺序释放的光可移动保护基及其在治疗释放中的应用

已经合成了基于双乙酰基咔唑的荧光可光去除保护基(FPRPG),该保护基用于依次释放两个不同的官能团,例如羧酸,醇,硫醇和胺。对合成药物递送系统(DDS)的研究证明了我们系统在体外的双重释放能力的适用性。
更新日期:2017-11-03
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