Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.,Cell Stem Cell

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Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.
Cell Stem Cell ( IF 19.8 ) Pub Date : 2017-Nov-02 , DOI: 10.1016/j.stem.2017.09.014
Roger A Barker ₁ , Malin Parmar ₂ , Lorenz Studer ₃ , Jun Takahashi ₄

Affiliation

Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era, with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons. As many groups have ongoing or completed GMP-level cell manufacturing, we highlight key clinical translation considerations from our recent fourth GForce-PD meeting.

中文翻译：

干细胞衍生的多巴胺神经元治疗帕金森病的人体试验：新时代的黎明。

以干细胞为基础的帕金森病疗法正在进入一个令人兴奋的新时代，几个研究小组正在对多能干细胞 (PSC) 衍生的多巴胺神经元进行临床试验。由于许多团队正在进行或完成了 GMP 级别的细胞制造，我们在最近的第四次 GForce-PD 会议中强调了关键的临床翻译考虑因素。

更新日期：2017-11-02

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