Preschool wheeze is a highly prevalent clinical problem [1] which, while typically mild, can present within a wide spectrum of severity and is associated with considerable healthcare costs [2]. The natural history is favourable and the majority of preschool wheezers will outgrow their symptoms regardless of any intervention [3–5]. However, a solid evidence base with which to guide clinicians as to which preschool wheezers would benefit from treatment, if any, is lacking. Multi-trigger and viral wheeze track over time but it is unclear whether they represent separate disease entities http://ow.ly/El7w30eO9fb

中文翻译：

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多触发和病毒性喘息：描述症状还是定义疾病？

学龄前喘息是一种非常普遍的临床问题 [1]，虽然通常是轻微的，但其严重程度范围很广，并且与相当大的医疗保健费用有关 [2]。自然史是有利的，无论采取任何干预措施，大多数学龄前喘息患者的症状都会消失[3-5]。然而，缺乏一个坚实的证据基础来指导临床医生确定哪些学龄前喘息症患者会从治疗中受益（如果有的话）。随着时间的推移，多触发和病毒性喘息跟踪但尚不清楚它们是否代表单独的疾病实体 http://ow.ly/El7w30eO9fb