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Eosinophilic Myocarditis as a Cause of Acute Cardiac Syndromes
Journal of the American College of Cardiology ( IF 21.7 ) Pub Date : 2017-11-01 , DOI: 10.1016/j.jacc.2017.09.022
Leslie T Cooper 1
Affiliation  

M yocarditis characterized by an eosinophilrich infiltrate was first associated with adverse drug reactions during the 1940s (1). The diagnosis was most often confirmed after clinical presentation of acute heart failure or sudden death (2). In the subsequent decades, multiple case reports and small case series described eosinophilic myocarditis (EM) in association with other disorders, including eosinophilic granulomatous polyangiitis (formerly Churg-Strauss syndrome), Loeffler endomyocardial disease, parasite infections, and idiopathic hypereosinophilic syndrome (3). Although the spectrum of clinical presentations associated with EM became remarkably broad, the prognosis remained poor.

中文翻译:

嗜酸性粒细胞性心肌炎是急性心脏综合征的原因

以嗜酸性粒细胞浸润为特征的心肌炎在 1940 年代首次与药物不良反应相关 (1)。诊断最常在急性心力衰竭或猝死的临床表现后得到确认 (2)。在随后的几十年中,多个病例报告和小型病例系列描述了与其他疾病相关的嗜酸性粒细胞性心肌炎 (EM),包括嗜酸性粒细胞性肉芽肿性多血管炎(以前称为 Churg-Strauss 综合征)、Loeffler 心内膜心肌病、寄生虫感染和特发性嗜酸性粒细胞增多综合征 (3) . 尽管与 EM 相关的临床表现范围变得非常广泛,但预后仍然很差。
更新日期:2017-11-01
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