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High performance photosensitizers with aggregation-induced emission for image-guided photodynamic anticancer therapy
Materials Horizons ( IF 13.3 ) Pub Date : 2017-08-18 00:00:00 , DOI: 10.1039/c7mh00469a
Wenbo Wu 1, 2, 2, 3, 4 , Duo Mao 1, 2, 3 , Shidang Xu 1, 2, 3 , Shenglu Ji 1, 2, 3 , Fang Hu 1, 2, 3 , Dan Ding 5, 6, 7, 8, 9 , Deling Kong 5, 6, 7, 8, 9 , Bin Liu 1, 2, 3, 10, 11
Affiliation  

A series of D–A′–π–A type photosensitizers, AP3 and AP4, were designed and synthesized to show strong aggregation-induced far red and near infrared emission and very effective 1O2 generation simultaneously. In comparison with the most widely used photosensitizer, Ce6 nanoparticles, AP4 nanoparticles showed over 10-fold higher fluorescence quantum yield, and more than 3-fold higher 1O2 generation efficiency, and have been successfully used for image-guided photodynamic anticancer therapy.

中文翻译:

具有聚集诱导发射的高性能光敏剂,用于图像引导的光动力抗癌治疗

设计并合成了一系列D–A'–π–A型光敏剂AP3AP4,以显示强聚集诱导的远红和近红外发射以及同时非常有效的1 O 2生成。与最广泛使用的光敏剂Ce6纳米颗粒相比,AP4纳米颗粒的荧光量子产率高10倍以上,1 O 2生成效率高3倍以上,已成功用于图像引导的光动力抗癌治疗。
更新日期:2017-10-30
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