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Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
Nature Structural & Molecular Biology ( IF 16.8 ) Pub Date : 2017-10-23 , DOI: 10.1038/nsmb.3487 Xueyin Wang , Richard D Paucek , Anne R Gooding , Zachary Z Brown , Eva J Ge , Tom W Muir , Thomas R Cech
Nature Structural & Molecular Biology ( IF 16.8 ) Pub Date : 2017-10-23 , DOI: 10.1038/nsmb.3487 Xueyin Wang , Richard D Paucek , Anne R Gooding , Zachary Z Brown , Eva J Ge , Tom W Muir , Thomas R Cech
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
中文翻译:
染色质中DNA募集PRC2的分子分析及其对RNA的抑制
染色质中DNA募集PRC2的分子分析及其对RNA的抑制
更新日期:2017-10-30
Nature Structural & Molecular Biology, Published online: 23 October 2017; doi:10.1038/nsmb.3487
Biochemical reconstitution of PRC2 interactions with chromatinized templates demonstrates that protein-free linker DNA dominates the PRC2-nucleosome interaction, while RNA inhibits binding.
中文翻译:
染色质中DNA募集PRC2的分子分析及其对RNA的抑制
染色质中DNA募集PRC2的分子分析及其对RNA的抑制
《自然结构与分子生物学》,在线发布:2017年10月23日;doi:10.1038 / nsmb.3487
PRC2相互作用与染色模板的生化重建表明,无蛋白的接头DNA主导PRC2核小体相互作用,而RNA抑制结合。