Four macrocyclic bis(pyrrolidino)fullerene regioisomers with e-edge, e-face, trans-4 and cis-2 addition patterns were synthesized from the corresponding monoadduct by Prato's cycloaddition in a yield of 50%, and fully characterized by spectroscopic techniques. Bisadduct regioisomers were isolated easily in a pure form using dry-flash column chromatography. The relative ratio of the isolated regioisomers e-edge/e-face/trans-4/cis-2 was 1.0:1.9:1.5:4.9. Morphology of self-assembled structures of the four bisadduct regioisomers in solution was characterized using scanning electron microscopy.

中文翻译：

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含有不对称双酰胺系链的富勒烯双加合物区域异构体

四个大环的二（吡咯烷基）区域异构体的富勒烯与ë _edge时，ê面取向，反式-4和顺-2除了图案，从相应的单加成物合成由普拉托环加成以50％的产率，并通过光谱技术完全表征。使用干快速柱色谱法可以很容易地以纯净形式分离双双加合物区域异构体。分离的区域异构体的相对比例ë _edge时/ ë -面/反式-4 /顺-2为1.0：1.9：1.5：4.9。使用扫描电子显微镜表征溶液中的​​四个双加合物区域异构体的自组装结构的形态。