Microwave-Assisted Generation and Capture by Azoles of ortho-Quinone Methide Intermediates under Aqueous Conditions,European Journal of Organic Chemistry

当前位置： X-MOL 学术 › Eur. J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Microwave-Assisted Generation and Capture by Azoles of ortho-Quinone Methide Intermediates under Aqueous Conditions
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-10-26 05:00:48 , DOI: 10.1002/ejoc.201701183
Silvia González-Pelayo ₁ , Luis A. López ₁

Affiliation

ortho-Quinone methides can be efficiently generated in water. Trapping with azoles provides a convenient route to alkylated azole derivatives, a class of heterocyclic compounds with potential applications in medicinal chemistry. This protocol does not require any activator for the generation of the reactive intermediate. No chromatographic purification is required in most cases.

中文翻译：