Silver-Catalyzed Decarboxylative Radical Addition/Cyclization of α,α-Difluoroarylacetic Acids with Acrylamides To Synthesize Difluorinated Oxindoles,European Journal of Organic Chemistry

当前位置： X-MOL 学术 › Eur. J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Silver-Catalyzed Decarboxylative Radical Addition/Cyclization of α,α-Difluoroarylacetic Acids with Acrylamides To Synthesize Difluorinated Oxindoles
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2017-10-27 04:27:59 , DOI: 10.1002/ejoc.201701248
Yin-Long Li _{1,

2} , Ji-Bo Wang ₂ , Xue-Lin Wang ₂ , Yang Cao ₂ , Jun Deng _{1,

2}

Affiliation

A series of difluorinated oxindoles that contain various functional groups have been synthesized by a silver-catalyzed decarboxylative radical addition/cyclization reaction between α,α-difluoroarylacetic acids and acrylamides. The mechanistic studies reveal that this transformation involves a free-radical pathway and the CF₂ group of the α,α-difluoroarylacetic acid plays a vital role.

中文翻译：