In this issue of the European Respiratory Journal, Dumas et al. [1] describe associations between occupational disinfectant exposure and asthma control in US nurses. Asthma control was defined by using the Asthma Control Test (ACT) and based on responses to five questions on activity limitations, frequency of symptoms and frequency of use of quick-relief medication in the past 4 weeks (β-agonist inhaler, e.g. albuterol, for symptom control). This instrument is not commonly considered an end-point in studies on occupational exposures and asthma, while asthma control is of particular relevance for asthma patients at work. Thus, the use of asthma control using the ACT is of particular interest [2]. According to the Global Initiative for Asthma Statement, asthma control is the extent to which manifestations of asthma can be observed, or have been reduced or removed by treatment. Asthma control has two dimensions; treatment of symptoms and future risk of adverse outcomes. Variables that can determine future adverse outcomes are lung function, exposure to allergens and non-specific stimuli (smoking, indoor and outdoor air quality), socio-economic and psychological problems, comorbidities and eosinophilia. These variables also determine future outcomes of occupational asthma. The ACT includes a limited set of these, in particular variables associated with treatment of symptoms. Poor control of asthma may be the result of ongoing exposure to disinfectants http://ow.ly/njzC30fJFMj

中文翻译：

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职业暴露与哮喘控制

在本期欧洲呼吸杂志中，Dumas 等人。[1] 描述了美国护士职业消毒剂暴露与哮喘控制之间的关联。哮喘控制是通过使用哮喘控制测试 (ACT) 来定义的，并基于对过去 4 周活动受限、症状频率和快速缓解药物使用频率（β-激动剂吸入剂，例如沙丁胺醇、沙丁胺醇、用于症状控制）。该工具通常不被视为职业暴露和哮喘研究的终点，而哮喘控制与工作中的哮喘患者特别相关。因此，使用 ACT 控制哮喘是特别令人感兴趣的 [2]。根据全球哮喘倡议声明，哮喘控制是可以观察到哮喘表现的程度，或已通过治疗减少或去除。哮喘控制有两个维度；症状的治疗和未来不良结果的风险。可以确定未来不良结果的变量是肺功能、接触过敏原和非特异性刺激（吸烟、室内和室外空气质量）、社会经济和心理问题、合并症和嗜酸性粒细胞增多症。这些变量也决定了职业性哮喘的未来结果。ACT 包括一组有限的这些变量，特别是与症状治疗相关的变量。哮喘控制不佳可能是持续接触消毒剂的结果 http://ow.ly/njzC30fJFMj 暴露于过敏原和非特异性刺激（吸烟、室内和室外空气质量）、社会经济和心理问题、合并症和嗜酸性粒细胞增多症。这些变量也决定了职业性哮喘的未来结果。ACT 包括一组有限的这些变量，特别是与症状治疗相关的变量。哮喘控制不佳可能是持续接触消毒剂的结果 http://ow.ly/njzC30fJFMj 暴露于过敏原和非特异性刺激（吸烟、室内和室外空气质量）、社会经济和心理问题、合并症和嗜酸性粒细胞增多症。这些变量也决定了职业性哮喘的未来结果。ACT 包括一组有限的这些变量，特别是与症状治疗相关的变量。哮喘控制不佳可能是持续接触消毒剂的结果 http://ow.ly/njzC30fJFMj