Despite advances in ART, implantation and pregnancy rates per embryo transfer still remain low. IVF laboratories strive to ensure that the process of handling gametes in vitro closely mimics the in vivo environment. However, there remains a lack of knowledge regarding the in vivo regulation and dynamic variation in biophysical parameters such as oxygen concentration, pH and temperature within the reproductive tract.

中文翻译：

---

女性生殖道中的体内氧气，温度和pH动态及其在人类受孕中的重要性：系统综述

尽管抗逆转录病毒疗法取得了进步，但每次胚胎移植的着床率和怀孕率仍然很低。体外受精实验室努力确保体外处理配子的过程紧密模拟体内环境。但是，关于体内调节和生殖道内诸如氧气浓度，pH和温度等生物物理参数的动态变化，仍然缺乏知识。