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A non-coding function of TYRP1 mRNA promotes melanoma growth
Nature Cell Biology ( IF 17.3 ) Pub Date : 2017-10-09 , DOI: 10.1038/ncb3623 David Gilot , Mélodie Migault , Laura Bachelot , Fabrice Journé , Aljosja Rogiers , Emmanuelle Donnou-Fournet , Ariane Mogha , Nicolas Mouchet , Marie-Laure Pinel-Marie , Bernard Mari , Tristan Montier , Sébastien Corre , Arthur Gautron , Florian Rambow , Petra El Hajj , Rania Ben Jouira , Sophie Tartare-Deckert , Jean-Christophe Marine , Brice Felden , Ghanem Ghanem , Marie-Dominique Galibert
Nature Cell Biology ( IF 17.3 ) Pub Date : 2017-10-09 , DOI: 10.1038/ncb3623 David Gilot , Mélodie Migault , Laura Bachelot , Fabrice Journé , Aljosja Rogiers , Emmanuelle Donnou-Fournet , Ariane Mogha , Nicolas Mouchet , Marie-Laure Pinel-Marie , Bernard Mari , Tristan Montier , Sébastien Corre , Arthur Gautron , Florian Rambow , Petra El Hajj , Rania Ben Jouira , Sophie Tartare-Deckert , Jean-Christophe Marine , Brice Felden , Ghanem Ghanem , Marie-Dominique Galibert
A non-coding function of TYRP1 mRNA promotes melanoma growth
中文翻译：
TYRP1 mRNA的非编码功能促进黑色素瘤生长
TYRP1 mRNA的非编码功能促进黑色素瘤生长
更新日期：2017-10-25
Nature Cell Biology, Published online: 9 October 2017; doi:10.1038/ncb3623
Gilot et al. have found that TYRP1 mRNA, in addition to coding for TYRP1 protein, can promote melanoma by sequestering the tumour suppressor miR-16, thus de-repressing the mRNA transcription of miR-16 target RAB17, which is involved in melanoma cell proliferation.
中文翻译：
TYRP1 mRNA的非编码功能促进黑色素瘤生长
TYRP1 mRNA的非编码功能促进黑色素瘤生长
《自然细胞生物学》，在线发布：2017年10月9日; doi：10.1038 / ncb3623
Gilot等。已经发现，除了编码TYRP1蛋白外，TYRP1 mRNA还可以通过隔离肿瘤抑制因子miR-16来促进黑色素瘤，从而抑制与黑色素瘤细胞增殖有关的miR-16靶标RAB17的mRNA转录。
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