Seven new naturally occurring barrigenol-like compounds, camellianols A–G (1–7), and 10 known triterpenoids were isolated from the twigs and leaves of the cultivated endangered ornamental plant Camellia crapnelliana. According to the ECD octant rule for saturated cyclohexanones, the absolute configurations of camellianols D (4) and E (5) were defined. The backbones of the remaining new isolates are assumed to have the same absolute configuration as compounds 4, 5, and harpullone (12). Compounds 2, 3, 9, 10, 13, and 16 exhibited inhibitory effects on the protein tyrosine phosphatase 1B (PTP1B) enzyme, with IC₅₀ values less than 10 μM.

中文翻译：

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茶花醇A–G，类似Barrigenol的三萜类化合物具有PTP1B抑制作用，来自濒危观赏植物茶花

七个新的天然存在barrigenol样化合物，camellianols A-G（1 - 7）和10个已知三萜类化合物是从栽培濒危观赏植物的枝条和叶子中分离红皮糙果茶。根据针对饱和环己酮的ECD八分法则，定义了茶油醇D（4）和E（5）的绝对构型。剩余的新分离物的主链被假定为具有相同的绝对构型的化合物4，5，和harpullone（12）。化合物2，3，9，10，13，以及16个对蛋白质酪氨酸磷酸酶1B（PTP1B）酶具有抑制作用，IC ₅₀值小于10μM。