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Histone H3 Dual Ubiquitylation Mediates Maintenance DNA Methylation
Molecular Cell ( IF 14.5 ) Pub Date : 2017-10-19 , DOI: 10.1016/j.molcel.2017.10.007
Kendra R. Vann , Tatiana G. Kutateladze

Epigenetic marks, including DNA methylation and posttranslational modifications (PTMs) in histones, are important factors in determining the fate of replicating cells. In this issue of Molecular Cell, Ishiyama et al. (2017) reveal yet another layer in a remarkably complex mechanism of maintenance DNA methylation.



中文翻译:

组蛋白H3双泛素化介导维持DNA甲基化

表观遗传标记,包括组蛋白中的DNA甲基化和翻译后修饰(PTM),是决定复制细胞命运的重要因素。在本期《分子细胞》中,石山等人。(2017)揭示了维持DNA甲基化非常复杂的机制中的另一层。

更新日期:2017-10-19
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