The overarching goal of pediatric oncologists is to cure while minimizing the likelihood of serious acute and long-term toxicities. To this end, the dramatic improvement in survival for patients with acute lymphoblastic leukemia (ALL) over the past 30 years is attributable to an enhanced understanding of leukemia biology and the development of a robust risk classification system designed to limit treatment intensity for those with an excellent prognosis when treated with standard therapies.

中文翻译：

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回复艾恩·科恩

儿科肿瘤学家的首要目标是在治愈的同时最大程度地降低严重急性和长期毒性的可能性。为此，在过去30年中，急性淋巴细胞白血病（ALL）患者的生存率有了显着提高，这归因于人们对白血病生物学的深入了解以及开发了一种强大的风险分类系统，该系统旨在限制患有白血病的白血病患者的治疗强度使用标准疗法治疗时，预后极好。