Patients with advanced sarcoidosis may develop pulmonary hypertension for a variety of reasons [1]. One of the earlier papers noting the incidence and severity of this problem came from the clinic run by Gianfranco Rizzato in Milan [2]. Despite the well documented association noted in that article, there were very few reports of sarcoidosis-associated pulmonary hypertension (S-APH) until 20 years later. Over the past 10 years, reports regarding S-APH have come from the USA [3–5], Europe [1, 6, 7] and Japan [8]. These studies found that S-APH was most frequently seen patients with fibrotic disease and was associated with increased mortality [9, 10]. More evidence that sarcoidosis patients with pulmonary hypertension respond to therapy http://ow.ly/H40c30fetN4

中文翻译：

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结节病相关肺动脉高压的治疗：如此接近，但到目前为止

晚期结节病患者可能因多种原因发生肺动脉高压[1]。早期的一篇论文指出了这个问题的发生率和严重程度，来自米兰的 Gianfranco Rizzato 经营的诊所 [2]。尽管在那篇文章中提到了有据可查的关联，但直到 20 年后才很少有结节病相关肺动脉高压 (S-APH) 的报告。在过去的 10 年中，关于 S-APH 的报道来自美国 [3-5]、欧洲 [1, 6, 7] 和日本 [8]。这些研究发现，S-APH 是最常见的纤维化疾病患者，并且与死亡率增加有关 [9, 10]。更多证据表明肺动脉高压结节病患者对治疗有反应 http://ow.ly/H40c30fetN4