Although the risk of developing cardiovascular disease (CVD) is reduced by the Mediterranean diet,1 CVD prevalence in Spain is rising. CVD is a major cause of mortality and morbidity in this country, and there is a growing awareness in the scientific community of the need for advances in knowledge, diagnosis, and therapy. Spain has a strong tradition of basic research in molecular biology, immunology, development, neuroscience, and oncology, but historically there have been few research groups dedicated to basic cardiovascular research, and this has been reflected in limited funding. Over the last 20 years, a national strategy to address this situation has seen the creation of a cardiovascular center of excellence and research networks focused on CVD. This significant boost to Spanish cardiovascular research has generated closer collaboration between the clinical and basic research communities, with already tangible beneficial results for patients. Here, we outline current trends in cardiovascular research in Spain, highlighting achievements, opportunities, and challenges. ### Grants and Funding Despite increasing CVD incidence and prevalence, public research funding in Spain has decreased over the last decade. This cut in funds follows a general trend in Spain in the wake of the global financial crisis. In 2016, the Ministry of Economy and Competitiveness, which is the main public funding body in Spain, spent around 380 million euros on different project grants, mainly in the so-called Excellence, Societal Challenges, and Health Research Projects programs. The Excellence call funded >700 grants (42% success rate), averaging around 100 000 euros per project. The Societal Challenges awarded 1500 grants (49% success rate) with 145 000 euros each on average. The Health Research Projects scheme funded >600 projects with an average of 95 000 euros each (36% success rate). These projects are 3 to 4 years long and were awarded to 1, or sometimes 2, principal investigators. Over the last …

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西班牙基础和转化性心血管研究的现状

尽管地中海饮食降低了患心血管疾病（CVD）的风险，但西班牙CVD的患病率正在上升。CVD是该国死亡率和发病率的主要原因，科学界对知识，诊断和治疗的需求日益增长。西班牙在分子生物学，免疫学，发育，神经科学和肿瘤学方面有着悠久的基础研究传统，但历史上很少有专门从事基础心血管研究的研究小组，这在有限的资金中得到了体现。在过去的20年中，针对这种情况的国家战略已经建立了心血管高级研究中心和专注于CVD的研究网络。西班牙心血管研究的显着发展已在临床和基础研究界之间建立了更紧密的合作关系，为患者带来了切实的有益结果。在这里，我们概述了西班牙心血管研究的最新趋势，重点介绍了成就，机遇和挑战。###赠款和资金尽管CVD发病率和患病率增加，但西班牙的公共研究资金在过去十年中有所减少。资金削减是在全球金融危机之后，西班牙出现大势所趋。2016年，西班牙主要的公共资助机构经济与竞争力部在各种项目赠款上花费了约3.8亿欧元，主要用于所谓的卓越，社会挑战和健康研究项目计划。卓越电话资助> 700笔赠款（成功率42％），平均每个项目10万欧元。“社会挑战赛”授予1500笔赠款（成功率49％），平均每笔赠款145 000欧元。卫生研究项目计划资助了600多个项目，每个项目平均9.5万欧元（成功率36％）。这些项目为期3至4年，被授予1位研究人员，有时还包括2位主要研究人员。在过去 …