当前位置: X-MOL 学术Nat. Cell Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
MK2 balances inflammation and cell death
Nature Cell Biology ( IF 17.3 ) Pub Date :  , DOI: 10.1038/ncb3619
Andrew Oberst

MK2 balances inflammation and cell death

Nature Cell Biology, Published online: 29 September 2017; doi:10.1038/ncb3619

The cytokine tumour necrosis factor (TNF) and the toll-like receptors (TLRs) coordinate immune responses by activating inflammatory transcriptional programs, but these signals can also trigger cell death. Recent studies identify the MAP kinase substrate MK2 as a key player in determining whether cells live or die in response to TNF and TLR signalling.



中文翻译:

MK2平衡炎症和细胞死亡

MK2平衡炎症和细胞死亡

《自然细胞生物学》(Nature Cell Biology),在线发布:2017年9月29日;doi:10.1038 / ncb3619

细胞因子肿瘤坏死因子(TNF)和Toll样受体(TLR)通过激活炎症转录程序来协调免疫反应,但这些信号也可能触发细胞死亡。最近的研究表明,MAP激酶底物MK2是确定细胞是否响应TNF和TLR信号而存活或死亡的关键因素。

更新日期:2017-10-12
down
wechat
bug