Neurodegenerative disorders take a heavy toll on individuals who have a diagnosis and their family and loved ones, and place an enormous economic burden on the health-care system. Parkinson's disease is amenable to reasonably, albeit incompletely, effective therapies to manage symptoms, but to date, no treatment has been found to slow its progression. Therefore, any potentially disease-modifying treatment is met with great enthusiasm.

中文翻译：

---

帕金森氏病的挑战和未兑现的承诺

神经退行性疾病给患有诊断的个人及其家人和亲人造成沉重的负担，并给医疗保健系统带来巨大的经济负担。帕金森氏病可以合理，尽管不完全有效地治疗症状，但是迄今为止，还没有发现能减缓其进展的治疗方法。因此，任何潜在的疾病缓解疗法都会引起极大的热情。