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Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B cell function and inhibition of the PD-1/PD-L1 pathway
Leukemia ( IF 12.8 ) Pub Date :  , DOI: 10.1038/leu.2017.304
K Kondo , H Shaim , P A Thompson , J A Burger , M Keating , Z Estrov , D Harris , E Kim , A Ferrajoli , M Daher , R Basar , M Muftuoglu , N Imahashi , A Alsuliman , C Sobieski , E Gokdemir , W Wierda , N Jain , E Liu , E J Shpall , K Rezvani

Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B cell function and inhibition of the PD-1/PD-L1 pathway

Leukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.304



中文翻译:

依鲁替尼通过STAT3介导的调节性B细胞功能抑制和PD-1 / PD-L1途径抑制来调节免疫抑制性CLL微环境

依鲁替尼通过STAT3介导的调节性B细胞功能抑制和PD-1 / PD-L1途径抑制来调节免疫抑制性CLL微环境

白血病,在线发布:2017年10月3日; doi:10.1038 / leu.2017.304

更新日期:2017-10-11
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