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Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin+ progenitors
Nature Neuroscience ( IF 21.2 ) Pub Date : 2017-08-14 00:00:00 , DOI: 10.1038/nn.4621 Alexandre Wojcinski , Andrew K Lawton , N Sumru Bayin , Zhimin Lao , Daniel N Stephen , Alexandra L Joyner
Nature Neuroscience ( IF 21.2 ) Pub Date : 2017-08-14 00:00:00 , DOI: 10.1038/nn.4621 Alexandre Wojcinski , Andrew K Lawton , N Sumru Bayin , Zhimin Lao , Daniel N Stephen , Alexandra L Joyner
Recovery of the developing cerebellum after depletion of granule cells, the most plentiful neuron population, depends on adaptive reprogramming of neural progenitors to a new fate and a powerful cell–cell communication system that ensures re-establishment of the correct proportions of different cerebellar cell types and normal circuit formation.
中文翻译:
Nestin +祖细胞的适应性重编程后损伤小脑颗粒细胞
颗粒细胞(最丰富的神经元种群)耗尽后,发育中的小脑的恢复取决于神经祖细胞对新命运的适应性重编程和功能强大的细胞-细胞通讯系统,该系统可确保不同小脑细胞类型正确比例的重建和正常的电路形成。
更新日期:2017-09-28
中文翻译:
Nestin +祖细胞的适应性重编程后损伤小脑颗粒细胞
颗粒细胞(最丰富的神经元种群)耗尽后,发育中的小脑的恢复取决于神经祖细胞对新命运的适应性重编程和功能强大的细胞-细胞通讯系统,该系统可确保不同小脑细胞类型正确比例的重建和正常的电路形成。