Animal navigation requires multiple types of information for decisions on directional heading. We identified neural processing channels that encode multiple cues during navigational decision-making in Drosophila melanogaster. In a flight simulator, we found that flies made directional choices on the basis of the location of a recently presented landmark. This experience-guided navigation was impaired by silencing neurons in the bulb (BU), a region in the central brain. Two-photon calcium imaging during flight revealed that the dorsal part of the BU encodes the location of a recent landmark, whereas the ventral part of the BU tracks self-motion reflecting turns. Photolabeling-based circuit tracing indicated that these functional compartments of the BU constitute adjacent, yet distinct, anatomical pathways that both enter the navigation center. Thus, the fly's navigation system organizes multiple types of information in parallel channels, which may compactly transmit signals without interference for decision-making during flight.

中文翻译：

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果蝇导航期间近期视觉体验和自我运动的并行编码

动物导航需要多种类型的信息来决定方向航向。我们确定了在果蝇导航决策过程中编码多个线索的神经处理通道。。在飞行模拟器中，我们发现苍蝇根据最近呈现的地标的位置做出了方向选择。这种经验指导的导航受到大脑中部区域灯泡（BU）中神经元沉默的影响。飞行过程中的双光子钙成像显示BU的背侧部分编码最近的标志性建筑的位置，而BU的腹侧部分跟踪自运动反射的转弯。基于光标记的电路跟踪表明，BU的这些功能隔室构成了相邻但又截然不同的解剖路径，两者均进入导航中心。因此，苍蝇的导航系统在并行通道中组织多种类型的信息，这些信息可以紧凑地传输信号而不会干扰飞行过程中的决策。