Glucose-responsive insulin by molecular and physical design

Nature Chemistry, Published online: 22 September 2017; doi:10.1038/nchem.2857

Glucose-responsive insulin is a therapeutic that modulates its potency, concentration or dosing relative to a patient’s dynamic glucose concentration. This Perspective summarizes some of the recent accomplishments in this field as well as discussing new computational algorithms that may aid in the development of such therapeutics.

中文翻译：

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通过分子和物理设计的葡萄糖反应性胰岛素

通过分子和物理设计的葡萄糖反应性胰岛素

Nature Chemistry，在线发布：2017年9月22日；doi：10.1038 / nchem.2857

葡萄糖反应性胰岛素是相对于患者动态葡萄糖浓度调节其效力，浓度或剂量的治疗剂。该观点总结了该领域的一些最新成就，并讨论了可能有助于此类疗法发展的新的计算算法。