Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH,Angewandte Chemie International Edition

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Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2017-09-22 02:20:25 , DOI: 10.1002/anie.201704084
Cai-Xia Yin ₁ , Kang-Ming Xiong ₁ , Fang-Jun Huo ₂ , James C. Salamanca ₃ , Robert M. Strongin ₃

Affiliation

Probing biothiols: Cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play crucial roles in human health. There are very few molecular probes and abiotic sensors that can simultaneously discriminate among biothiols. Recent progress on probes featuring multiple binding sites to distinguish Cys, Hcy, and GSH is summarized, and a variety of unmet critical needs and opportunities for chemists in the thiol probe field are discussed.

中文翻译：

具有多个结合位点的荧光探针，用于区分Cys，Hcy和GSH

探测生物硫醇：半胱氨酸（Cys），高半胱氨酸（Hcy）和谷胱甘肽（GSH）在人类健康中起着至关重要的作用。很少有分子探针和非生物传感器可以同时区分生物硫醇。总结了具有多个结合位点以区分Cys，Hcy和GSH的探针的最新进展，并讨论了硫醇探针领域化学家的各种未满足的关键需求和机会。

更新日期：2017-09-22

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