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Is gabapentin effective for women with unexplained chronic pelvic pain?
The BMJ ( IF 105.7 ) Pub Date : 2017-09-21 , DOI: 10.1136/bmj.j3520
Andrew W Horne , Katy Vincent , Roman Cregg , Jane Daniels

This article is linked with a commentary on “What to do in the light of this uncertainty” by James Duffy. #### What you need to know Chronic pelvic pain in women is a common presentation in primary care. Pain persists or recurs over at least six months1 and can be distressing, affecting physical function, quality of life, and productivity.2 Nearly 38 per 1000 women are affected annually in the UK. Global estimates range from 2.1% to 24% of the female population.34 Endometriosis, adenomyosis, adhesions, pelvic inflammatory disease, irritable bowel syndrome, bladder pain syndrome, nerve entrapment, and musculoskeletal pain are among the common causes.45 These are often identified by screening for pelvic infection (eg, Chlamydia trachomatis ), pelvic imaging (eg, ultrasound, magnetic resonance imaging), and diagnostic laparoscopy.1 Some 40%-55% of women with chronic pelvic pain in secondary care appear to have no obvious underlying pathology based on clinical history, examination, and investigations.46 Management of this group of women is challenging and there are few established gynaecological treatments. The Royal College of Obstetricians and Gynaecologists recommends a combination of pharmacological interventions, physiotherapy, and cognitive behavioural therapy.1 Often women try several methods sequentially or in combination.478Figure 1⇓ presents a common diagnostic and treatment approach that women with chronic pelvic pain might be offered. Fig 1  Flow diagram showing the possible “treatment journey” (and timelines) for a woman who presents to primary care with …

中文翻译:

加巴喷丁对患有无法解释的慢性骨盆痛的妇女有效吗?

本文与詹姆斯·达菲(James Duffy)对“鉴于这种不确定性该怎么办”的评论相关联。####您需要了解的女性慢性盆腔痛是基层医疗中的常见表现。疼痛持续或复发至少六个月1,并可能令人痛苦,影响身体机能,生活质量和生产力。2在英国,每年每1000名妇女中有近38人受到影响。全球估计占女性人口的2.1%到24%。34子宫内膜异位,子宫腺肌病,粘连,盆腔炎,肠易激综合征,膀胱疼痛综合征,神经压迫和肌肉骨骼疼痛是常见原因。45通常可以确定这些原因。通过筛查骨盆感染(例如沙眼衣原体),骨盆成像(例如超声,磁共振成像)和诊断性腹腔镜检查。1根据临床病史,检查和调查,在二级保健中约40%-55%的慢性盆腔痛妇女似乎没有明显的潜在病理学。46该组妇女的治疗具有挑战性,几乎没有妇科治疗方法。皇家妇产科学院建议将药理学干预,物理疗法和认知行为疗法相结合。1妇女通常会依次或联合尝试几种方法。478图1⇓提出了一种常见的诊断和治疗方法,即患有慢性盆腔痛的妇女可能是提供。图1流程图显示了一名以……接受初级保健的妇女可能的“治疗历程”(和时间表)
更新日期:2017-09-21
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