Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase,Organic & Biomolecular Chemistry

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Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2017-09-14 00:00:00 , DOI: 10.1039/c7ob02171b
Apan Qian _{1,

2,

3,

4,

5} , Huang Shi _{1,

2,

3,

4,

5} , Runlang Zhu _{1,

2,

3,

4,

5} , Jiatao Yan _{1,

2,

3,

4,

5} , Wen Li _{1,

2,

3,

4,

5} , Kun Liu _{1,

2,

3,

4,

5} , Afang Zhang _{1,

2,

3,

4,

5}

Affiliation

Monodisperse thermoresponsive cyclodextrins appended with benzenesulfonamides were demonstrated to reversibly regulate the enzymatic activity of carbonic anhydrase, which was found to be dependent on both scaffold effect and thermoresponsiveness.

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