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Lipidated polymers for the stabilization of cubosomes: nanostructured drug delivery vehicles
Chemical Communications ( IF 4.9 ) Pub Date : 2017-08-25 00:00:00 , DOI: 10.1039/c7cc05842j
James L. Grace 1, 2, 3, 4, 5 , Nicolas Alcaraz 1, 2, 3, 4, 5 , Nghia P. Truong 1, 2, 3, 4, 5 , Thomas P. Davis 1, 2, 3, 4, 5 , Ben J. Boyd 1, 2, 3, 4, 5 , John F. Quinn 1, 2, 3, 4, 5 , Michael R. Whittaker 1, 2, 3, 4, 5
Affiliation  

Lipidated polymers, like their protein counterparts, may be useful in fields as diverse as biochemistry and drug delivery. As such, strategies for preparing lipidated polymers with defined molecular architecture are clearly warranted. Herein, we describe a broadly-applicable methodology for synthesizing such lipidated materials, and demonstrate how they can be applied to the preparation of nanostructured drug delivery vehicles.

中文翻译:

用于稳定小脂质体的脂化聚合物:纳米结构的药物递送载体

像它们的蛋白质对应物一样,脂化聚合物可能在生物化学和药物递送等多种领域中有用。因此,显然有必要制备具有确定的分子结构的脂化聚合物的策略。在本文中,我们描述了合成此类脂化材料的广泛应用的方法,并展示了它们如何可用于制备纳米结构的药物递送载体。
更新日期:2017-09-21
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