Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity,Blood

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Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity
Blood ( IF 21.0 ) Pub Date : 2017-09-21 , DOI: 10.1182/blood-2017-03-772996
Marie Roelens _{1,

2,

3} , Marc Delord _{2,

4} , Caroline Ram-Wolff _{2,

5,

6} , Anne Marie-Cardine _{2,

5} , Antonio Alberdi _{2,

7} , Guitta Maki ₃ , Laurence Homyrda ₃ , Armand Bensussan _{2,

5} , Martine Bagot _{2,

5,

6} , Antoine Toubert _{1,

2,

3} , Hélène Moins-Teisserenc _{1,

2,

3}

Affiliation

To the editor: Sezary syndrome (SS) is a rare, aggressive leukemic form of primary cutaneous T-cell lymphoma.[1][1] The diagnostic criteria associate a clonal T-cell receptor (TCR) rearrangement with peripheral Sezary cell (SC) counts of ≥1 G/L, an increased CD4/CD8 ratio of ≥10, CD4+CD7−

中文翻译：

循环和皮肤来源的 Sézary 细胞：克隆但具有表型可塑性

致编辑：Sezary 综合征 (SS) 是一种罕见的侵袭性白血病形式的原发性皮肤 T 细胞淋巴瘤。[1][1] 诊断标准将克隆性 T 细胞受体 (TCR) 重排与外周 Sezary 细胞 (SC) 计数≥1 G/L、CD4/CD8 比率增加≥10、CD4+CD7−

更新日期：2017-09-21

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