Severe burn injuries are the most traumatic and physically debilitating injuries affecting nearly every organ system and leading to significant morbidity and mortality. Early burn wound excision and skin grafting are common clinical practices that have significantly improved the outcomes for severe burn injured patients by reducing mortality rate and days of hospital stay. However, slow wound healing, infection, pain, and hypertrophic scarring continue to remain a major challenge in burn research and management. In the present article, we review and discuss issues in the current treatment of burn injuries; the advances and novel strategies developed in the past decade that have improved burn management; and also, pioneer ideas and studies in burn research which aims to enhance burn wound care with a focus on burn wound infection, pain management, treatments for scarring and skin tissue engineering.

严重的烧伤是最伤人，最使身体衰弱的伤害，几乎影响每个器官系统，并导致明显的发病率和死亡率。早期烧伤创面切除和皮肤移植是常见的临床实践，通过降低死亡率和住院天数，显着改善了严重烧伤患者的预后。然而，缓慢的伤口愈合，感染，疼痛和肥厚性瘢痕形成仍然是烧伤研究和治疗中的主要挑战。在本文中，我们回顾并讨论当前烧伤治疗中的问题。过去十年中取得的进步和新颖的策略改善了烧伤管理；以及烧伤研究的先驱思想和研究，旨在加强烧伤伤口护理，重点是烧伤伤口感染，疼痛管理，