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B cell autoimmunity at the extremes
Nature Immunology ( IF 27.7 ) Pub Date : , DOI: 10.1038/ni.3840 Julie Zikherman , Clifford A Lowell
Nature Immunology ( IF 27.7 ) Pub Date : , DOI: 10.1038/ni.3840 Julie Zikherman , Clifford A Lowell
B cell autoimmunity at the extremes
中文翻译:
极端情况下的B细胞自身免疫
极端情况下的B细胞自身免疫
更新日期:2017-09-21
Nature Immunology, Published online: 19 September 2017; doi:10.1038/ni.3840
Caveolin-1 has a critical role in orchestrating the membrane organization of B cells. In its absence, signaling via the B cell antigen receptor and B cell tolerance are impaired, which results in autoimmunity.
中文翻译:
极端情况下的B细胞自身免疫
极端情况下的B细胞自身免疫
《自然免疫学》,在线发布:2017年9月19日; doi:10.1038 / ni.3840
Caveolin-1在协调B细胞的膜组织中起关键作用。在缺少它的情况下,通过B细胞抗原受体的信号传导和B细胞耐受性会受损,从而导致自身免疫。