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Evolving Models of Heterochromatin: From Foci to Liquid Droplets
Molecular Cell ( IF 14.5 ) Pub Date : 2017-09-19 , DOI: 10.1016/j.molcel.2017.08.022 Antonis Tatarakis , Reza Behrouzi , Danesh Moazed
中文翻译:
异染色质的进化模型:从焦点到液滴。
更新日期:2017-09-19
Molecular Cell ( IF 14.5 ) Pub Date : 2017-09-19 , DOI: 10.1016/j.molcel.2017.08.022 Antonis Tatarakis , Reza Behrouzi , Danesh Moazed
Two recent papers (Larson et al., 2017, Strom et al., 2017) in Nature propose that heterochromatic domains are organized into phase-separated liquid compartments. Here we highlight the main findings that support the liquid-like nature of HP1 domains and discuss their functional implications in gene silencing and genome organization.
中文翻译:
异染色质的进化模型:从焦点到液滴。
Nature上的两篇最新论文(Larson等,2017,Strom等,2017)提出,异色域被组织成相分离的液体区室。在这里,我们重点介绍支持HP1域类似液体性质的主要发现,并讨论它们在基因沉默和基因组组织中的功能含义。