To the Editor: Denic et al. (June 15 issue)1 found a fairly constant single-nephron glomerular filtration rate (GFR) among kidney donors, even with declining numbers of nephrons in persons younger than 70 years of age. It is unclear whether there was a correlation between the number of nephrons and the single-nephron GFR in an analysis adjusted for demographic characteristics and other variables. It would be informative if the authors examined their data using such adjustments. Low birth weight has been associated with chronic kidney disease in adolescents2 and adults.3,4 Low birth weight has been shown to be associated with a . . .

中文翻译：

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健康成年人的单肾小球肾小球滤过率

致编辑：Denic等。（6月15日发行）1发现，即使在70岁以下的人中肾单位数量下降，肾脏供体中的单肾单位肾小球滤过率（GFR）也相当稳定。尚不清楚在针对人口统计学特征和其他变量进行调整的分析中，肾单位数目和单肾单位肾小球滤过率之间是否存在相关性。如果作者使用这种调整来检查他们的数据，那将是有益的。低出生体重与青少年和成人慢性肾脏疾病有关.3,4。低出生体重与慢性肾病有关。。。