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Combination therapy for bloodstream infections with carbapenemase-producing Enterobacteriaceae – Authors' reply
The Lancet Infectious Diseases ( IF 56.3 ) Pub Date : 2017-10-01 , DOI: 10.1016/s1473-3099(17)30522-4
Belén Gutiérrez-Gutiérrez , Robert A Bonomo , Yehuda Carmeli , David L Paterson , Alvaro Pascual , Jesús Rodríguez-Baño

We thank Bernd Salzberger and Gerd Fätkenheuer for their interest in our study.1 They were concerned about the use of Charlson, Pitt, and INCREMENT-CPE scores, as well as the individual variables contained in them in the analyses. Our objective was to provide the best possible estimation of the association of the main exposure (treatment) with the outcome considering the effect of confounders, in accordance with the study hypothesis; we did not intend to provide a model to predict outcome (mortality).

中文翻译:

产生碳青霉烯酶的肠杆菌科细菌对血流感染的联合治疗–作者的回复

感谢Bernd Salzberger和GerdFätkenheuer对我们的研究感兴趣。1他们担心使用Charlson,Pitt和INCREMENT-CPE评分,以及分析中包含的各个变量。我们的目标是根据研究假设,考虑混杂因素的影响,提供对主要暴露(治疗)与预后的关联的最佳估计。我们无意提供预测结果(死亡率)的模型。
更新日期:2017-09-20
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