A versatile platform for adding functional properties to amyloid fibrils,Organic & Biomolecular Chemistry

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A versatile platform for adding functional properties to amyloid fibrils
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2017-09-14 00:00:00 , DOI: 10.1039/c7ob02042b
Devon F. A. Fontaine _{1,

2,

3,

4} , Valerie A. Ivancic _{1,

2,

3,

4} , Michael B. Reardon _{1,

2,

3,

4} , Noel D. Lazo _{1,

2,

3,

4} , Charles E. Jakobsche _{1,

2,

3,

4}

Affiliation

Herein we report the design, synthesis, and testing of prototype members of a family of amyloid-binding molecular tools that can manipulate the fibrils by giving them various new functional properties. Potential applications include manipulating disease-relevant fibrils, developing novel functional nanomaterials, and studying the molecular details of fibril structures.

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