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A four-step tandem synthesis of 3,5-diaroyl-4-arylpyrazoles from 1,3-diaryl-propane-1,3-diketones
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2017-09-19 , DOI: 10.1016/j.tetlet.2017.09.050
Jianlan Zhang , Wenwen Chen , Dayun Huang , Xiaobao Zeng , Xinyan Wang , Yuefei Hu

A novel four-step tandem procedure was developed for efficient synthesis of 3,5-diaroyl-4-arylpyrazoles by simply stirring the mixture of 1,3-diarylpropane-1,3-diketones, TsN3, aqueous MeNH2 and Na2CO3 in DMF at 85 °C for 3 h.



中文翻译:

由1,3-二芳基丙烷-1,3-二酮四步串联合成3,5-二氮酰基-4-芳基吡唑

通过简单地搅拌1,3-二芳基丙烷-1,3-二酮,TsN 3,MeNH 2水溶液和Na 2 CO的混合物,开发了一种新颖的四步串联程序,可高效合成3,5-二氮酰基-4-芳基吡唑3在DMF中在85℃下3小时。

更新日期:2017-09-19
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