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Revealing a Role for NMDA Receptors in Regulating STN Inputs following the Loss of Dopamine.
Neuron ( IF 16.2 ) Pub Date : 2017-Sep-13 , DOI: 10.1016/j.neuron.2017.08.041
Aphroditi A. Mamaligas , Christopher P. Ford

In this issue of Neuron, Chu et al. (2017) show that dopamine depletion using a 6-OHDA model causes a decrease in hyperdirect inputs from the motor cortex directly to the STN and that rescuing this loss alleviates Parkinsonian symptoms.

中文翻译:

揭示NMDA受体在多巴胺丧失后调节STN输入中的作用。

在本期《神经元》中,Chu等人。(2017)表明,使用6-OHDA模型消耗多巴胺会导致运动皮层直接输入到STN的超直接输入减少,挽救这种损失可缓解帕金森氏症。
更新日期:2017-09-20
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