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Developing Neutrophils Must Eat…Themselves!
Immunity ( IF 25.5 ) Pub Date : 2017-09-19 , DOI: 10.1016/j.immuni.2017.08.013
Zhichao Fan , Klaus Ley

In this issue of Immunity, Riffelmacher et al. (2017) show that autophagy is necessary for the release of free fatty acids from intracellular stores within neutrophil precursor cells. This limits glycolysis, increases oxidative phosphorylation, and is essential for neutrophil maturation.



中文翻译:

发展中性粒细胞必须吃……自己!

在本期《免疫》中,Riffelmacher等人。(2017)表明自噬是中性粒细胞前体细胞内细胞内游离脂肪酸释放所必需的。这限制了糖酵解,增加了氧化磷酸化,并且对于嗜中性白细胞的成熟是必不可少的。

更新日期:2017-09-19
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