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Initial symptom severity of bipolar I disorder and the efficacy of olanzapine: a meta-analysis of individual participant data from five placebo-controlled studies.
The Lancet ( IF 168.9 ) Pub Date : 2017-Nov-01 , DOI: 10.1016/s2215-0366(17)30331-0
Myrto T Samara , Yair Goldberg , Stephen Z Levine , Toshi A Furukawa , John R Geddes , Andrea Cipriani , John M Davis , Stefan Leucht

The efficacy of antipsychotics across the initial severity range in patients with acute mania remains unclear. Therefore, we examined the influence of baseline severity on the efficacy of olanzapine.

中文翻译:

I型双相情感障碍的初始症状严重程度和奥氮平的疗效:一项来自五项安慰剂对照研究的个体参与者数据的荟萃分析。

尚不清楚在最初的严重程度范围内抗精神病药在急性躁狂症患者中的疗效。因此,我们检查了基线严重程度对奥氮平疗效的影响。
更新日期:2017-09-20
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