In this work, a novel nanohybrid (AuPtNPs/S-NS-GR) of well-defined Au-Pt bimetallic nanoparticles (Au-PtNPs) decorated on sulfonated nitrogen sulfur co-doped graphene (S-NS-GR) was developed. Firstly, nitrogen sulfur co-doped graphene (NS-GR) was synthesized by one-step thermal annealing method. Secondly, phenyl SO₃H- group was introduced onto the surface of NS-GR via diazotization reaction, which could provide more binding sites for the formation of metal nanoparticles. Finally, Au-Pt bimetallic nanoparticles were anchored on the surface of S-NS-GR by using electrochemical deposition. The prepared material was characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDS), Raman spectroscopy and electrochemical impedance spectra (EIS). In addition, the electrocatalytic activity towards dopamine (DA) and uric acid (UA) was systematically studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. Under optimum conditions, the linear ranges for the detection of DA and UA were 1.0×10⁻⁸ – 4.0×10⁻⁴ M and 1.0×10⁻⁶ – 1.0×10⁻³ M with the limits of detection (LOD, S/N = 3) of 0.006 μM and 0.038 μM, respectively. Furthermore, the modified electrode was applied to real sample analysis.

在这项工作中，开发了一种新型的纳米杂化物（AuPtNPs / S-NS-GR），该杂化物是在磺化氮硫共掺杂石墨烯（S-NS-GR）上修饰的轮廓分明的Au-Pt双金属纳米颗粒（Au-PtNPs）。首先，通过一步热退火法合成了氮硫共掺杂石墨烯（NS-GR）。其次，苯基SO ₃H-基团通过重氮化反应引入到NS-GR的表面，可以为金属纳米颗粒的形成提供更多的结合位点。最后，通过电化学沉积将Au-Pt双金属纳米颗粒固定在S-NS-GR的表面上。通过扫描电子显微镜（SEM），X射线光电子能谱（XPS），能量色散X射线能谱（EDS），拉曼光谱和电化学阻抗谱（EIS）来表征所制备的材料。此外，通过循环伏安法（CV）和微分脉冲伏安法（DPV）技术系统地研究了对多巴胺（DA）和尿酸（UA）的电催化活性。在最佳条件下，用于检测DA和UA的线性范围为1.0 × 10 ^-8 – 4.0× 10 ^-4 M和1.0 × 10 ^-6 – 1.0 × 10 ^-3 M，检出限（LOD，S / N = 3）分别为0.006μM和0.038μM。此外，将修饰的电极应用于真实样品分析。