Caveolin-1 has a critical role in orchestrating the membrane organization of B cells. In its absence, signaling via the B cell antigen receptor and B cell tolerance are impaired, which results in autoimmunity.

中文翻译：

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极端情况下的B细胞自身免疫

Caveolin-1在协调B细胞的膜组织中起关键作用。在缺少它的情况下，通过B细胞抗原受体的信号传导和B细胞耐受性会受损，从而导致自身免疫。