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Preconditioned cues have no value
eLife ( IF 7.7 ) Pub Date : 2017-09-19 , DOI: 10.7554/elife.28362
Melissa J Sharpe 1, 2, 3 , Hannah M Batchelor 1 , Geoffrey Schoenbaum 1, 4, 5, 6
Affiliation  

Sensory preconditioning has been used to implicate midbrain dopamine in model-based learning, contradicting the view that dopamine transients reflect model-free value. However, it has been suggested that model-free value might accrue directly to the preconditioned cue through mediated learning. Here, building on previous work (Sadacca et al., 2016), we address this question by testing whether a preconditioned cue will support conditioned reinforcement in rats. We found that while both directly conditioned and second-order conditioned cues supported robust conditioned reinforcement, a preconditioned cue did not. These data show that the preconditioned cue in our procedure does not directly accrue model-free value and further suggest that the cue may not necessarily access value even indirectly in a model-based manner. If so, then phasic response of dopamine neurons to cues in this setting cannot be described as signaling errors in predicting value.

中文翻译:

预处理的线索没有价值

感觉预处理已被用于在基于模型的学习中暗示中脑多巴胺,这与多巴胺瞬变反映无模型价值的观点相矛盾。然而,有人提出无模型价值可能会通过中介学习直接产生于预处理线索。在这里,在之前的工作(Sadacca 等人,2016 年)的基础上,我们通过测试预处理线索是否支持大鼠的条件强化来解决这个问题。我们发现,虽然直接条件和二阶条件线索都支持强大的条件强化,但预处理线索却没有。这些数据表明,我们程序中的预处理线索不会直接产生无模型价值,并进一步表明线索可能不一定以基于模型的方式间接访问价值。如果是这样的话,
更新日期:2017-09-19
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