Fragile X mental retardation protein (FMRP) represses the transcription of many target genes, including genes that encode chromatin-associated proteins. Loss of FMRP leads to fragile X syndrome (FXS); however, whether misregulation of chromatin-associated proteins contributes to FXS is unclear. Korb et al. showed that

中文翻译：

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神经发育障碍：靶向转录的目标

脆弱的X智力低下蛋白（FMRP）抑制许多靶基因的转录，包括编码染色质相关蛋白的基因。FMRP的丢失会导致脆性X综合征（FXS）；然而，尚不清楚染色质相关蛋白的失调是否会导致FXS。Korb等。表明