A highly sensitive sensor is strategically designed for bisphenol A (BPA) detection. To enable the sensor to meet the requirements of sensitivity and selectivity, dendritic platinum nanoparticles (DPNs) with a high surface area were prepared and directly coated on gold nanoparticles deposited on a screen-printed carbon electrode, followed by the deposition of a polyethyleneimine-phosphatidylcholine (PEI-PC) layer. The PEI-PC layer protects the sensor against interference effects (such as from ascorbic acid, acetaminophen, uric acid, and dopamine) and further enhances the sensitivity. With our sensor, we were able to detect the presence of bisphenol A precisely at the oxidation potential of 0.270 V. The sensor performance in BPA detection using amperometry under the optimized experimental conditions was demonstrated to reveal the two wide dynamic ranges of 0.01–1.0 μM and 1.0 μM–300 μM, with correlation coefficients of 0.9957 and 0.9864, respectively. The detection limit (DL) for BPA was determined to be 6.63 ± 0.77 nM. To examine its reliability, the sensor was evaluated for the detection of BPA in tap water through a recovery study, which paves the way for practical applications.

高度敏感的传感器经过战略性设计，可用于双酚A（BPA）检测。为使传感器满足灵敏度和选择性的要求，制备了具有高表面积的树枝状铂纳米颗粒（DPN），并将其直接涂覆在丝网印刷碳电极上沉积的金纳米颗粒上，然后沉积聚乙烯亚胺-磷脂酰胆碱（PEI-PC）层。PEI-PC层可保护传感器免受干扰影响（例如抗坏血酸，对乙酰氨基酚，尿酸和多巴胺），并进一步提高灵敏度。使用我们的传感器，我们能够在0.270 V的氧化电位下精确检测到双酚A的存在。在优化的实验条件下，使用安培法检测BPA的传感器性能被证明具有0.01-1.0μM和1.0μM-300μM的两个宽动态范围，相关系数分别为0.9957和0.9864。BPA的检出限（DL）被确定为6.63±0.77 nM。为了检查其可靠性，通过回收研究对传感器进行了评估以检测自来水中的BPA，这为实际应用铺平了道路。