The development of methods for the stereoselective synthesis of polysubstituted 1,3-dienes is a challenge to synthetic chemistry. Herein is reported a selective approach for the synthesis of polysubstituted 1,3-dienes using the ruthenium hydride catalyzed intramolecular silylvinylation of alkynes under 80 psi of ethylene gas. This strategy affords a single diene isomer, is applicable to substrates with aryl and alkyl substitution at the propargyl and homopropargyl positions, and has been utilized in the synthesis of 5- and 6-membered oxasilacycles.

中文翻译：

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氢化钌在80 psi的乙烯气氛下催化末端炔烃的甲硅烷基乙烯基化

立体选择性合成多取代的1，3-二烯的方法的发展对合成化学提出了挑战。本文报道了在80psi的乙烯气体下使用氢化钌催化炔烃的分子内甲硅烷基乙烯基化来合成多取代的1，3-二烯的选择性方法。该策略提供了单一的二烯异构体，适用于在炔丙基和均炔丙基位置具有芳基和烷基取代的底物，并已用于合成5和6元氧杂硅环。